Mental Health & Psychiatry in Downtown Sioux Falls, SD
Looking for a therapist or psychiatric provider in downtown Sioux Falls? MWI Health brings behavioral health, counseling, medication management, a substance use IOP, and Spravato together in one clinic on North Main Avenue. Help for anxiety, depression, ADHD, and more, and you can start soon.
Welcome to MWI Health
Compassionate mental health care, when you need it most
When you are struggling, the hardest part is often just knowing where to turn. MWI Health is a trusted behavioral health clinic in downtown Sioux Falls, SD, bringing therapy, medication management, and psychiatric care together under one roof on North Main Avenue. Whether you are searching for a caring therapist or a provider who truly listens, our team meets you with a plan built around you, not a one-size-fits-all protocol.
You do not have to keep waiting for things to feel better on their own. Our providers offer anxiety therapy, depression counseling, ADHD care, psychotherapy, a substance use IOP, and Spravato, with prompt availability and no referral needed. The sooner you reach out, the sooner you can start feeling more like yourself.
From mental health counseling in downtown Sioux Falls to expert psychiatric care, MWI Health also cares for the surrounding communities of Harrisburg, Brandon, and Tea, in person and by secure telehealth. New patients are welcome now. Call (605) 800-7477 to take the first step today.
Meet our founder
A personal welcome from Dr. Pavlis
Choosing a mental health provider is a big step, and it helps to know who is behind the care. In this short introduction, Dr. Clay J. Pavlis shares why he founded MWI Health and the individualized, judgment-free approach our downtown Sioux Falls team brings to every visit.
Services
Comprehensive behavioral health, in one place
Therapy, psychiatric care, and medication management under one roof, plus a substance use IOP and Spravato for treatment-resistant depression.
Why MWI Health
A local clinic built around you, not a directory listing
When you search for a therapist or psychiatric provider in downtown Sioux Falls, you deserve a real team you can see in person, not just a name on a list.
Experienced provider team
Psychiatric nurse practitioners and licensed clinicians who take the time to listen and build a plan around you.
Prompt availability
New patients welcome with no referral needed, so you are not waiting months to be seen.
Care in one place
Therapy, medication management, a substance use IOP, and Spravato, coordinated by one team.
In-person or telehealth
See us at our downtown clinic or from home by secure telehealth across SD, ND, and IA.
Conditions
What our team helps with
From anxiety and depression to ADHD and substance use, our team treats the whole picture, not just one symptom.
Your care team
Meet the downtown Sioux Falls providers
Real, named clinicians you will actually see, with specialties across psychiatry, therapy, and substance use care.
Psychiatric Providers
Therapy Team
Office Support Team
Patient reviews
Trusted by the Sioux Falls community
Real feedback from patients who started care with our downtown team.
"I've only been going here for a short time but I absolutely LOVE MWI! I was one of those people who thought going to a psychiatrist and therapy was rubbish. In the short time I've been going I have learned A LOT about myself, and my life seems to have turned around. I will ALWAYS choose MWI! Shout-out to the front desk, the nurse, and Shannon. Thank you for always being so kind and welcoming."
"I'd recommend them to anyone. They call me by name and have helped me a lot in the short time I've been going there."
"I have really bad anxiety, especially in those types of situations, but I left that all at the door. As soon as I walked in I was made to feel really comfortable, and it was the same with every person I met with that day. Everybody there is super nice, really genuine and caring. I continue to go back now."
In the news
Our downtown opening, covered locally
Argus Leader
How MWI Health is expanding mental health support
Read the story →
Coverage
Insurance accepted
We accept most major plans and verify your benefits before your first visit.
Good to know
Downtown Sioux Falls questions, answered
We are at 317 North Main Avenue, Suite 100, Sioux Falls, SD 57104. We serve Sioux Falls, Harrisburg, Brandon, Tea, and surrounding communities.
Yes. Our downtown psychiatric nurse practitioners and therapists are accepting new patients now, often with prompt availability. No referral is needed, so you do not have to wait. Call (605) 800-7477 to get started today.
MWI Health accepts most major insurance plans, including Cigna, Aetna, Blue Cross Blue Shield, Medicare, and Tricare. Our team verifies your benefits before your first visit. Call (605) 800-7477 to confirm your coverage.
Yes. Our downtown clinic offers an Intensive Outpatient Program for substance use, led by SUD-credentialed facilitators. Participation requires a primary substance use disorder diagnosis; co-occurring mental health conditions are treated as part of integrated care.
Yes. Spravato (esketamine) is available for eligible patients with treatment-resistant depression, given in a monitored, in-office setting.
Our providers care for patients across a wide range of ages, and services vary by clinician. When you call (605) 800-7477, our team will match you or your child with a provider whose scope and availability fit your needs.
Yes. In addition to in-person visits at our downtown clinic, we offer secure telehealth appointments for patients across South Dakota, North Dakota, and Iowa. Ask our team which option is the best fit when you schedule.
Our downtown team often has prompt availability, and no referral is required. The fastest way to find the soonest opening is to call (605) 800-7477 or request an appointment through our patient portal.
Please bring your insurance card, a valid photo ID, a list of any current medications and dosages, and any relevant records from previous mental health providers. Arriving a few minutes early gives you time to complete intake paperwork.
Yes. Your care at MWI Health is private and protected under HIPAA. We use a secure patient portal for records, messaging, and results, and your information is only shared as permitted by law or with your consent.
Service area
Proudly serving the Sioux Falls area
Our downtown clinic welcomes patients from across the metro and nearby communities, in person and by secure telehealth.
Visit us
Find our downtown Sioux Falls clinic
Conveniently located on North Main Avenue in downtown Sioux Falls, with easy access for the surrounding communities.
MWI Health, Downtown Sioux Falls
Sioux Falls, SD 57104
Medically reviewed
Reviewed by Clay J. Pavlis, MD
Board-certified psychiatrist and Chief Medical Officer of MWI Health.
Start care with a downtown Sioux Falls team you can trust
New patients are welcome now for therapy, medication management, and psychiatric care. No referral needed, and we verify your insurance before your first visit. In-person and telehealth appointments available, so do not wait to feel better.
In a crisis
Get help right now
MWI Health is an outpatient clinic and cannot respond to emergencies. If you or someone you know is in danger or thinking about suicide, use these free, confidential resources, available 24/7.
- Call 911Life-threatening emergency, or someone at immediate risk of harm.
- Call or text 988Suicide & Crisis Lifeline, 24/7. Chat at 988lifeline.org/chat. In South Dakota, answered locally by the Helpline Center.
- Dial 988, then press 1Veterans Crisis Line, or text 838255.
- Dial 2-1-1Helpline Center, everyday support and resources. Call 211 or text your ZIP code to 898211.