Substance use & recovery

Substance Use Treatment in Downtown Sioux Falls

Recovery is possible, and you do not have to do it alone. Our team offers a full range of substance use treatment, from outpatient care to a structured intensive outpatient program, close to home in Sioux Falls or by virtual visits.

Board-certified psychiatric care Serving SD, ND & Iowa New patients welcome, no referral needed In-person & telehealth

Understanding substance use disorder

A clear path forward, at your pace

Substance use disorder is a medical condition, not a lack of willpower. It changes how the brain handles reward and stress, which is why stopping on your own can be so hard. With the right support, recovery is very possible.

Treatment is not one size. It ranges from outpatient support to a structured intensive outpatient program (IOP), medication-assisted treatment, and integrated care for co-occurring mental health conditions. We help match you to the right level of care.

The language here is meant to be plain and calm, because reaching out is hard enough. No referral is required, and we will walk you through what to expect before you start.

Signs & symptoms

When it may be time to reach out

If several of these feel familiar, a confidential conversation with our team can help you understand your options.

Using more or longer than intendedStrong cravingsTrouble cutting backContinued use despite problemsNeglecting responsibilitiesNeeding more for the same effectWithdrawal when stoppingGiving up activities you valuedUse that strains relationships

Our approach

Substance use treatment options

Psychiatry and therapy under one roof, coordinated by a team that communicates about your care.

1. Confidential assessmentWe start with a private conversation to understand what is going on and what kind of support fits your situation.
2. Outpatient and intensive outpatient careCare ranges from regular outpatient visits to our structured intensive outpatient program (IOP) in Downtown Sioux Falls, matched to what you need.
3. Medication-assisted treatmentWhen appropriate, medication can ease cravings and withdrawal and support your recovery, managed by our providers.
4. Support for co-occurring conditionsAnxiety, depression, and trauma are treated alongside substance use as part of integrated care.

Where to find care

Substance use care in Downtown Sioux Falls

Our licensed substance use intensive outpatient program is based at our Downtown Sioux Falls clinic, with virtual IOP options available.

South Dakota

Downtown Sioux Falls

317 North Main Avenue, Suite 100
Sioux Falls, SD 57104
Mon–Fri, 8:00am–5:00pm

Why MWI Health

A local team built around you

Board-certified psychiatry

Led by a board-certified psychiatrist and Chief Medical Officer, with an experienced provider team.

Prompt availability

New patients welcome with no referral needed, so you are not waiting months to be seen.

Care in one place

Therapy and psychiatric care coordinated by one team that talks to each other about your plan.

In-person or telehealth

See us at one of our clinics or from home by secure telehealth across SD, ND, and IA.

Coverage

Insurance accepted

We accept most major plans and verify your benefits before your first visit.

AetnaBlue Cross Blue ShieldCignaUnitedHealthcareHumanaMedicareand more, verified before your visit

Good to know

Substance use treatment questions, answered

We offer a range of care, from outpatient visits to a structured intensive outpatient program (IOP), medication-assisted treatment, and integrated care for co-occurring mental health conditions. Our team helps match you to the right level.

No referral is needed. You can reach out directly and we will start with a confidential assessment.

Yes. Your care and your information are kept confidential, in line with health privacy laws.

Yes. When appropriate, our providers use medication to ease cravings and withdrawal as part of a broader recovery plan.

Yes. We offer virtual IOP options for patients in our region, alongside in-person care in Downtown Sioux Falls.

We aim to see new patients quickly. Reach out and we will help you get started without a long wait.

We accept most major insurance plans and verify your benefits before you begin.

Clay J. Pavlis, MD, Chief Medical Officer of MWI Health

Medically reviewed

Reviewed by Clay J. Pavlis, MD

Board-certified psychiatrist and Chief Medical Officer of MWI Health.

Meet Dr. Pavlis Last reviewed August 2026

In a crisis

Get help right now

MWI Health is an outpatient clinic and cannot respond to emergencies. If you or someone you know is in danger or thinking about suicide, use these free, confidential resources, available 24/7.

  • Call 911Life-threatening emergency, or someone at immediate risk of harm.
  • Call or text 988Suicide & Crisis Lifeline, 24/7. Chat at 988lifeline.org/chat. In South Dakota, answered locally by the Helpline Center.
  • Dial 988, then press 1Veterans Crisis Line, or text 838255.
  • Dial 2-1-1Helpline Center, everyday support and resources. Call 211 or text your ZIP code to 898211.

Recovery is possible, and you do not have to do it alone

Our team is accepting new patients across South Dakota, North Dakota, and Iowa, in person and by telehealth. No referral needed.

Substance Use TreatmentMWI Health
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