Treatment-Resistant Depression Care in South Dakota, North Dakota & Iowa
If antidepressants have not worked, it does not mean nothing will. Our psychiatric team offers advanced options for depression that has not responded, including Spravato and TMS, in a monitored setting.
Understanding treatment-resistant depression
When antidepressants have not been enough
Treatment-resistant depression usually means you have tried two or more antidepressants at adequate doses without meaningful relief. It is more common than many people realize, and it does not mean you are out of options.
At MWI Health, we start by reviewing what you have already tried, then discuss advanced options. These include Spravato, a nasal spray form of esketamine approved for treatment-resistant depression and given in a monitored, in-office setting, and TMS therapy, a non-invasive treatment offered at our Sioux Falls clinic.
These advanced options are offered at our Sioux Falls clinic, with secure telehealth available for evaluation and follow-up across South Dakota, North Dakota, and Iowa. No referral is required to get started.
Signs & symptoms
Signs your depression may be treatment-resistant
If these sound familiar, advanced options may be worth discussing with a psychiatric provider.
Our approach
How we treat depression that has not responded
Psychiatry and therapy under one roof, coordinated by a team that communicates about your care.
Where to find care
Advanced depression care in Sioux Falls
Spravato and TMS therapy for treatment-resistant depression are offered at our Sioux Falls clinic, with secure telehealth for evaluation and follow-up across South Dakota, North Dakota, and Iowa.
Sioux Falls
Sioux Falls, SD 57106
Why MWI Health
A local team built around you
Board-certified psychiatry
Led by a board-certified psychiatrist and Chief Medical Officer, with an experienced provider team.
Prompt availability
New patients welcome with no referral needed, so you are not waiting months to be seen.
Care in one place
Therapy and psychiatric care coordinated by one team that talks to each other about your plan.
In-person or telehealth
See us at one of our clinics or from home by secure telehealth across SD, ND, and IA.
Coverage
Insurance accepted
We accept most major plans and verify your benefits before your first visit.
Good to know
Treatment-resistant depression questions, answered
It generally means depression that has not improved after trying two or more antidepressants at adequate doses and duration. It is common, and advanced options can still help.
Spravato is a nasal spray form of esketamine, approved by the FDA for treatment-resistant depression. It is given in a monitored, in-office setting with follow-up by our team.
Yes. TMS is a non-invasive, FDA-cleared treatment for depression, offered at our Sioux Falls clinic. It uses magnetic pulses to stimulate areas of the brain involved in mood.
No referral is needed. You can request an appointment directly, and we will review your history to see which options fit.
Evaluation and follow-up can be done by secure telehealth in South Dakota, North Dakota, and Iowa. Spravato and TMS are delivered in person at our Sioux Falls clinic.
Spravato and TMS therapy for treatment-resistant depression are offered at our Sioux Falls clinic. Evaluation and follow-up are available by telehealth across South Dakota, North Dakota, and Iowa.
We accept most major insurance plans and verify your benefits before your first visit.
Medically reviewed
Reviewed by Clay J. Pavlis, MD
Board-certified psychiatrist and Chief Medical Officer of MWI Health.
If you need help now
Support is available right away
MWI Health provides scheduled outpatient care and is not an emergency service. If you or someone you love is in crisis, reach out to one of these free, confidential resources.
- 988 Suicide & Crisis LifelineCall or text 988, any time, day or night.
- Crisis Text LineText HOME to 741741.
- EmergencyIf there is immediate danger, call 911.
If other treatments have not worked, there are still options
Our team is accepting new patients across South Dakota, North Dakota, and Iowa, in person and by telehealth. No referral needed.